ANALGESIA-EFFECTING 5-HYDROXYTRYPTOPHAN DERIVATIVES

摘要

Analgesia-effecting 5-hydroxytryptophan derivatives are disclosed of the formulae: I and II wherein R is selected from the group consisting of C2-C16 alkyl, C3-C8 cycloalkyl, C2-C16 alkenyl, C2-C16 alkynyl, aryl containing up to 14 carbon atoms, and arylalkyl containing up to 20 carbon atoms; R1 and R1a are each H or methyl; R2 and R2a are each H or R, as defined above; R3 and R3a are each H or alkyl containing from 1 to 4 carbons; R4 and R4a are each H or alkyl containing from 1 to 4 carbons; and their non-toxic, pharmacologically acceptable acid addition salts.