| 摘要 |
PURPOSE:To obtain the titled compound useful as a thrombus-dissolving agent from a cell obtained by purifying an enzymatic animal meat hydrolysate peptone without effect to the cell by a trace substance which is not concerned in the formation, by using a specific substance. CONSTITUTION:A specific plasminogen-activating factor is produced from a cell having said factor-producing ability in large quantities, by using said factor- inducing substance (referred to as A) purified from an enzymatic animal meat hydrolysate peptone. A liquid eluted in the range of a partition coefficient of 0.65-0.95 or an eluate having relative eluate amount of 2.0-2.7 in the gel filtration chromatography using Sephacryl S. 200 (Pharmacia A.B) and/or a solution eluted in a range of a partition coefficient of 0.18-0.66 or a eluate of a relative eluate amount of 1.2-1.8 in a gel filtration chromatography using Sephadex G-25 are used as a A. |
