发明名称 PRODUCTION OF L-ALPHA-METHYLPHENYLALANINES
摘要 PURPOSE:To obtain the titled compound useful as a raw material for producing hypotensor, etc., industrially advantageously, by treating a DL-alpha- methylphenylalaninamide with a cell of Mycobacterium methanolica or a treated material thereof and asymmetrically hydrolyzing. CONSTITUTION:A DL-alpha-methylphenylalaninamide shown by formula I (R<1> and R<2> are H, lower alkyl or R<1> and R<2> are mutually bonded to form 5-6-membered ring) is treated with a cell of Mycobacterium metanolica (FERM-P8823, etc.) of a treated material thereof and an L-alpha-methylphenylalaninamide is asymmetrically hydrolyzed to give an L-alpha-methylphenylalanine shown by formula II.
申请公布号 JPS63123398(A) 申请公布日期 1988.05.27
申请号 JP19860266760 申请日期 1986.11.11
申请人 MITSUBISHI GAS CHEM CO INC 发明人 URAGAMI SADAJI;KOGA HIROMI;KONDO TOSHIO;DOTANI MASAHARU
分类号 C12P13/22;C12P41/00;C12R1/32 主分类号 C12P13/22
代理机构 代理人
主权项
地址