发明名称 ERODIBLE MATRIX FOR SUSTAINED RELEASE BIOACTIVE COMPOSITION
摘要 A sustained release composition for releasing a biologically active compound into an aqueous liquid environment comprises said biologically active compound dispersed in a bioerodible matrix, the matrix comprising a mixture of 5 to 95% by weight of a polyethylene glycol having a molecular weight of from about 1000 to about 20,000, and 95 to 5% by weight of an erosion rate modifier which is an amphiphilic compound insoluble in the aqueous liquid. Dosage forms comprising the erodible matrix are prepared by molding, particularly by injection molding.
申请公布号 AU573149(B2) 申请公布日期 1988.05.26
申请号 AU19850046388 申请日期 1985.07.17
申请人 ZETACHRON, INC., 发明人 WALLACE C. SNIPES
分类号 A01N25/10;A61K9/00;A61K9/20;A61K9/22;A61K9/26;C05G3/00;(IPC1-7):A61K9/26;A61K33/14;A61K31/04;A61K31/60;A61K31/135;A61K31/19;A61K31/445;A61K31/47;A01N25/08;A01N47/22;A61K31/34;A61K31/54;A61K31/505;A61K31/40;A61K31/415;A61K31/52 主分类号 A01N25/10
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