发明名称 |
ANTIVIRAL PURINE DERIVATIVES |
摘要 |
Compounds of the general formula <CHEM> (wherein X is sulphur or oxygen or a chemical bond; R<1> is halogen, amino or azido; R<2> is hydrogen, hydroxy, alkyl or hydroxyalkyl; R<3> is hydrogen or alkyl; R<4> is hydroxy, hydroxyalkyl, benzyloxy, phosphate or carboxypropionyloxy; R<5> is hydrogen, alkyl or hydroxyalkyl) and salts and esters thereof, have been found to have valuable antiviral activity particularly against herpes viruses. Methods for the preparation of the above compounds are described as well as pharmaceutical formulations containing such compounds. |
申请公布号 |
DE3376325(D1) |
申请公布日期 |
1988.05.26 |
申请号 |
DE19833376325 |
申请日期 |
1983.10.13 |
申请人 |
THE WELLCOME FOUNDATION LIMITED |
发明人 |
SCHAEFFER, HOWARD JOHN;KRENITSKY, THOMAS ANTHONY;BEAUCHAMP, LILIA MARIE |
分类号 |
C07D473/32;A61K31/52;A61P31/12;A61P31/22;C07D473/00;C07D473/24;C07D473/40;C07F9/547;(IPC1-7):C07D473/32 |
主分类号 |
C07D473/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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