摘要 |
PURPOSE:To remove a surplus oily matter and an incomplete liposome by providing the refining part of a liposome suspension, the feeding mechanism for feeding the liposome suspension to the refining part and the controlling mechanism for controlling the temp. of a reactor to the optimum temp. to the titled apparatus. CONSTITUTION:The apparatus body has a cylindrical shape and is connected with major equipments of 1-5 after sterilizing them. In the major equipments 1-5, 4 is the reactor, 2, 3 are hollow chambers (the refining parts) provided an ultrafiltration and an auxiliary filter and 5 is a pressure type syringe (the feeding mechanism). And the liposome suspension is produced by accommodating the liposome preparation in the reactor 4 the temp. of which is controlled, followed by agitating while bubbling it with inert gas. And the obtd. liposome suspension is refined by passing it to the refining parts 2, 3 composed of the ultrafiltration and the auxiliary filter. |