Aotus interspecies hybridomas and monoclonal receptors produced thereby

摘要

Aotus trivirgatus interspecies hybridomas, their monoclonal receptors and methods of preparation and use are disclosed. The hybridomas are prepared by fusion of Aotus antibody-producing cells with myeloma cells containing about an equal number of chromosomes per cell. The resulting hybridomas are stable and secrete Aotus receptors. Particular receptors that immunoreact with antigenic proteins of Plasmodium falciparum shizonts and merozoites are disclosed.