摘要 |
A newly discovered pancreatic hormone, called ''pancreastatin'', and biologically active fragments thereof. These polypeptides inhibit glucose-induced secretion of insulin and somatostatin. Polyclonal and monoclonal antibodies to these peptides and pancreastatin antagonist are also described together with diagnostic and therapeutic compositions and methods that employ pancreastatin, its biologically active fragments, or antagonists/antibodies to pancreastatin or such fragements. |