发明名称 FUSED HETEROCYCLIC TETRAHYDROAMINOQUINOLINOLS AND RELATED COMPOUNDS,A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
摘要 There are disclosed compounds of the formula <CHEM> where =X-Y- is = @@S-, =N-@@, =CH-N=CH- or = @@O-, R4 being loweralkyl and R5 being hydrogen or loweralkyl, -Z- is - @- or -@@- , n is 1, 2 or 3, R1 and R2 are each independently hydrogen, loweralkyl or arylloweralkyl, and R3 is hydrogen or loweralkyl, with the proviso that when =X-Y-is =N- @@ , n is 2 or 3, R1 is hydrogen and R2 is hydrogen or loweralkyl, Z is not - @-, which compounds are useful for enhancing memory and for treating Alzheimer's disease.
申请公布号 ZA8708763(B) 申请公布日期 1988.05.19
申请号 ZA19870008763 申请日期 1987.11.23
申请人 HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED 发明人 GREGORY MICHAEL SHUTSKE;KEVIN J. KAPPLES
分类号 A61K31/47;A61P25/02;A61P25/28;C07D471/04;C07D491/048;C07D495/04;C07D498/04 主分类号 A61K31/47
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