| 摘要 |
NEW MATERIAL:A compound shown by the formula I [A is CH=CH-CO, CH= CH-CH2, group shown by the formula II, COO-(CH3)2; R1 and R2 are alkyl, form ethylene or propylene; R is pyrrolidinoalkyl-carbonyl, pyrrolidinocarbonylalkyl, alkoxycarbonylalkyl, trimethoxycinnamyl, etc.]. EXAMPLE:N,N'-Dimethyl-N-(1-pyrrolidinocarbonylmethyl)-N'-(3,4,5-trimet hoxycinnamoyl)-ethylenediamine. USE:Having vasodilating actions, antiarrhythmic actions, etc., useful as a circulatory organ type drug. PROCESS:A compound shown by the formula III (X is halogen) is reacted with a compound shown by the formula IV in a proper solvent (e.g., benzene, THF, etc.) in the presence of a deoxidizer, e.g., triethylamine, K2CO3, etc., to give a compound shown by the formula I. |
