| 摘要 |
PURPOSE:To produce the titled substance in high yield, by cultivating yeast belonging to the genus Saccharomyces by continuously or intermittently adding a carbon source, a nitrogen source and a phosphoric acid source to a medium in a culture bath in the production of the titled substance by using the yeast. CONSTITUTION:Yeast such as Saccharomyces cerevisiae, etc., belonging to the genus Saccharomyces, capable of producing riboflavin, is inoculated into a medium containing a carbon source such as glucose, acetic acid, ethanol, etc., a nitrogen source such as ammonium sulfate, peptone, urea, etc., and a phosphoric acid source such as phosphate, etc. The culture is carried under an aerobic condition out by continuously and intermittently supplying the consumed carbon source, nitrogen source and phosphate source. Riboflavin is collected from the prepared culture solution by a well-known method. |
