| 摘要 |
The invention pertains to copolymers activated for bonding of biologically active compounds and to a method for preparation thereof. Soluble and biodegradable copolymers activated for bonding of biologically active compounds which have their main chain formed from units of aspartic acid or glutamic acid, or both, or also from units of other amino acids, according to the general formula I <IMAGE> (I) where n is 1 or 2, m is 1 or 2, a+b+c is 100, a is 0.5 to 100, b is 0 to 99.5, c is 0 to 80; the substituent R1 is -NH-NH2, -N 3BOND N or <IMAGE> where x is 2 to 6, R2 is -NH(CH2)xOH where x=2 to 6; and R3 is methyl, 2-propyl, 2-methylpropyl, butyl, 2-butyl, benzyl or 4-hydroxybenzyl, and the molecular weight is 5,000 to 1,000,000.
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