摘要 |
PURPOSE:To obtain the titled compound useful as an anticonvulsant in high purity and yield, by reacting di-(2-thienyl).(N-methyl-5-methoxy-3-piperidylidene) methane with an organic acid methyl ester. CONSTITUTION:Di-( 2-thienyl ).(N-methyl-5-methoxy-3-piperidylidene)methane is reacted with an organic acid methyl ester expressed by the formula M-CH3 [M is X-COO (X is halogen), tosyloxy or methyloxy] to provide a quaternary salt of di-(2-thienyl).(N,N-dimethyl-5-methoxy-3-piperidylidene)methane or hydrate thereof.
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