| 摘要 |
2-Hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-ter-butylaminoethyl)-pyridine and its salts(I), useful as bronchial dilating agent, were prepd. Thus, 2-phenyl-6-(1-hydroxy-2-ter- butylaminoethyl)-4H-pyrido(3, 2-d)-1, 3-dioxine was reacted with maleic acid in the presence of org. solvent to give 2-phenyl-6-(1-hydroxy-2-ter-butylaminoethyl)-4H-pyrido(3, 2-d)-1, 3-dioxane maleate(II). The intermediate(II) was reacted with hydrogen chloride to give I.
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