发明名称 |
FREMGANGSMAATE FOR FREMSTILLING AV TERAPEUTISK AKTIVE HETEROCYKLISKE KETONER. |
摘要 |
The invention provides a series of novel heterocyclic ketones of formula I <CHEM> and pharmaceutically acceptable base-addition salts thereof, in which the values of R<4>, L, A, X and Q have the meanings defined in the following specification. The compounds of formula I are inhibitors of human leukocytic elastase. The invention also provides pharmaceutical compositions containing a compound of formula I, or a pharmaceutically acceptable base-addition salt thereof, and processes and intermediates for the manufacture of compounds of formula I. |
申请公布号 |
NO882036(D0) |
申请公布日期 |
1988.05.10 |
申请号 |
NO19880002036 |
申请日期 |
1988.05.10 |
申请人 |
ICI AMERICAS INC |
发明人 |
EDWARDS, PHILIP DUKE;LEWIS, JOSEPH JAMES;PERKINS, CHARLES WILLIAM;TRAINOR, DIANE AMY;WILDONGER, RICHARD ALAN |
分类号 |
A61K38/55;A61K31/422;A61K31/423;A61K31/428;A61P7/00;A61P11/00;A61P29/00;C07D207/04;C07D263/00;C07D413/12;C07D417/12;C07K1/02;C07K1/06;C07K1/113;C07K5/00;C07K5/06;C07K5/062;C07K5/08;C07K14/81;C12N9/99 |
主分类号 |
A61K38/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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