发明名称 SALT OF DICLOFENAC WITH A CYCLIC ORGANIC BASE AND PHARMACEUTICAL COMPOSITIONS WHICH CONTAIN IT
摘要 The salt of diclofenac with a cyclic organic base is prepared by dissolving diclofenac in a suitable organic solvent, adding said cyclic organic base, reacting the two components together, removing the solvent and crystallising the product obtained. Said salt is water soluble to an extent from 20% w/v to an extent exceeding 50% w/v, and is used to prepare pharmaceutical compositions preferably in granular form for use by dissolving in water for oral administration.
申请公布号 ZA8708405(B) 申请公布日期 1988.05.05
申请号 ZA19870008405 申请日期 1987.11.09
申请人 ALTERGON S.A. 发明人 ANTONIA ZIGGIOTTI;MICHELE DI SCHIENA
分类号 C07D295/02;A61K31/205;A61K31/40;A61K31/435;A61K31/4465;A61K31/45;A61P29/00;C07C67/00;C07C227/00;C07C229/42;C07D295/08;C07D295/088 主分类号 C07D295/02
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