发明名称 TWO PHASE FORMULATION COMPRISING NIFEDIPINE
摘要 In the treatment of cardiovascular and coronary disorders by administering to a patent suffering therefrom a solid preparation comprising nifedipine, the improvement which comprises administering such nifedipine in the form of a solid two-phase medicament formulation comprising a nifedipine coprecipitate, in which the nifedipine is present in a non-crystalline form, and crystalline nifedipine, whereby the nifedipine rapidly enters the blood stream in a relatively high concentration which is maintained for a relatively long time.
申请公布号 PH21989(A) 申请公布日期 1988.05.02
申请号 PH19940000306 申请日期 1984.05.18
申请人 BAYER AG 发明人 HEGASY AHMED;RUPP ROLAND;RAMSCH KLAUS-DIETER;LUCHTENBERG HELMUT
分类号 A61K9/00;A61K9/14;A61K9/22;A61K31/44;A61K47/32;A61K47/38;C07D211/90 主分类号 A61K9/00
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