| 摘要 |
NEW MATERIAL:A compound expressed by formula I [Z is OH or R<3>-CO-CH2- COO- (R<3> is alkyl, cycloalkyl or alkoxyalkyl); A is alkylene; B is -N(R<6>)2, formula II (R<6> and R<7> are H, alkyl, cycloalkyl, aralkyl, aryl or pyridyl; Ar is aryl or pyridyl; n is 0-2). EXAMPLE:2-(p-Dimethylaminophenyl) ethylacetoacetate. USE:A synthestic intermediate of dihydropyridine derivative useful as a medicine, etc. PREPARATION:A compound expressed by formula III is reacted with a compound expressed by formula R<6>-E (E is halogen) in a solvent such as N,N- dimethylformamide, etc., preferably in the presence of alkali salt at 10-120 deg.C for 1-5hr to provide a compound expressed by formula I [Z is OH, when B is N(R<6>)2]. |
