发明名称 ANALOGIFREMGANGSMAADE TIL FREMSTILLING AF AMINOALKOHOLDERIVATER ELLER FARMACEUTISKE ACCEPTABLE SALTE DERAF
摘要 Aminoalcohol derivatives corresponding to the formula (I) <IMAGE> in which Q is a group <IMAGE> and the other substituents have the meaning shown in Claim 1 are prepared by reaction with a compound of formula I, in which Q represents a group <IMAGE> or <IMAGE>, with an amine of type R3R4NH, Z being a halogen. The alcohol can then be esterified by reaction with an acid or an anhydride as defined in Claim 1. The compounds obtained have activities on the cardiovascular system, for example antihypertensive and/or antispasmodic activities, peripheral vasodilative activity, protective activity against myocardial anoxia, hypolipidemiating activity, antithrombotic activity, beta -lytic activity or platelet aggregation inhibiting activity, and/or activity on the central nervous system, for example a tranquillising activity.
申请公布号 DK151330(C) 申请公布日期 1988.04.25
申请号 DK19760005170 申请日期 1976.11.17
申请人 CONTINENTAL PHARMA INC. 发明人 LAMBELIN, GEORGES;ROBA, JOSEPH;GILLET, CLAUDE;RONCUCCI, ROMEO
分类号 A61K31/13;A61K31/135;A61K31/195;A61K31/215;A61K31/22;A61K31/335;A61K31/38;A61K31/381;A61K31/382;A61K31/395;A61K31/435;A61K31/495;A61K31/535;A61K31/54;A61P3/06;A61P9/00;A61P9/08;A61P9/12;A61P25/26;B01J23/00;B01J25/00;B01J27/00;B01J31/00;C07B61/00;C07C67/00;C07C213/00;C07C215/38;C07C217/56;C07C219/22;C07C225/16;C07C233/43;C07C233/73;C07C233/78;C07C255/24;C07C255/30;C07C255/58;C07C271/16;C07C311/01;C07C313/00;C07C323/25;C07C323/27;C07C323/32;C07C323/33;C07C323/41;C07C323/49;C07C323/62;C07D209/08;C07D211/14;C07D265/30;C07D265/36;C07D307/79;C07D327/06;C07D333/54;C07D335/06;C07D337/06;C07D337/08;C07D339/08;C07D405/06;C07D409/06;C07D409/12;(IPC1-7):C07C91/23;C07C93/06;C07D211/22;C07D307/77;C07D333/52;C07D335/08;C07D413/06 主分类号 A61K31/13
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