6-BETA-(ALPHA-ETHERIFIED OXYIMINO)-ACYLAMINO PENICILLANIC-ACID DERIVATIVES, THEIR PREPARATION AND USE

摘要

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt or in-vivo hydrolysable ester thereof: (I) wherein R1 is hydrogen or an amino protecting group and R is substituted methyl; optionally substituted C2-12 alkyl, alkenyl or alkynyl; carbocyclyl; aryl or heterocyclyl. These compounds have antibacterial properties, and therefore are of use in the treatment of bacterial infections in humans and animals caused by a wide range of organisms.