Method for the preparation of fibrates

摘要

The present invention relates to a method for the preparation of fibrates of the formula I according to the mechanism: <IMAGE> +TR <IMAGE> in which R1 represents especially a halogen atom (in particular F, Cl or Br, the preferred halogen atom being Cl) or an acetyl, (4-chlorophenyl)hydroxymethyl, 4-chlorobenzoyl or 2-(4-chlorobenzamido)ethyl group and R2 represents a C1-C4 alkyl group in which the hydrocarbon chain is linear or branched, the reaction V+VI being carried out without a solvent.