BENZODIAZEPINE RECEPTORS AND THEIR PREPARATION

摘要

New oxadiazolyl-imidazo-[1,4]benzodiazepine derivatives having benzodiazepine receptor activity have the formula R' is hydrogen, chlorine, fluorine or nitro in the 7- or 8-position, R1 is hydrogen or lower alkyl of up to 3 carbon atoms, R3 is the oxadiazolyl grouping of the formula wherein R'' is lower alkyl with up to 3 carbon atoms and A B is a grouping of the formula wherein R5 is hydrogen or methyl and R''' is hydrogen or chlorine. The compounds possess valuable pharmacological properties. In particular, they act on the central nervous system and are suitable for use in psychopharmaceutical preparations.