发明名称 FREMGANGSMAATE VED DYRKING AV LEUKOCYTER.
摘要 In accordance with the present invention, a method of culturing lymphocytes is disclosed in which the lymphocytes are cultured in the presence of interleukin-2 (IL-2) and an antibody to a lymphocyte surface receptor, preferably an antibody to a lymphocyte T3 surface receptor. Preferably, the antibody is monoclonal. Cells cultured with anti-CD3 maintain their LAK activity as they increase in number. The cells can also be cultured in the presence of an additional lymphokine to obtain additional LAK activity. Methods of medical treatment are also disclosed in which cells cultured in accordance with the culturing methods of the present invention are introduced into the individual to be treated.
申请公布号 NO881491(A) 申请公布日期 1988.04.07
申请号 NO19880001491 申请日期 1988.04.07
申请人 REGENTS OF THE UNIVERSITY OF MINNESOTA 发明人 OCHOA, AUGUSTO C.;ALTER, BARBARA J.;SONDEL, PAUL M.;BACH, FRITZ H.
分类号 C12N;C12N5/00;C12N5/02;C12N5/0783;(IPC1-7):C12N5/00 主分类号 C12N
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