| 发明名称 |
RENIN INHIBITORS CONTAINING 5-AMINO-2,5-DISUBSTITUTED-4-HYDROXYPENTANOIC ACID RESIDUES |
| 摘要 |
A series of novel polypeptide derivatives, containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues, which are useful for inhibiting the angiotensinogen-cleaving action of the enzyme renin. Particularly valuable precursors for many of these compounds are certain other 5-amino-2,5-disubstituted-4-hydroxypentanoic acid derivatives. |
| 申请公布号 |
ZA8605975(B) |
申请公布日期 |
1988.03.30 |
| 申请号 |
ZA19860005975 |
申请日期 |
1986.08.08 |
| 申请人 |
PFIZER INC. |
发明人 |
JASJIT SINGH BINDRA;EDWARD FOX KLEINMAN;ROBERT LOUIS ROSATI |
| 分类号 |
C07D405/12;A61K;A61K31/365;A61K31/47;A61K31/472;A61K38/00;A61K38/55;A61P9/12;A61P43/00;C07B31/00;C07B53/00;C07C67/00;C07C231/12;C07C233/47;C07C237/10;C07C237/16;C07C237/22;C07C239/00;C07C269/00;C07C269/06;C07C271/22;C07C279/04;C07D;C07D207/16;C07D215/08;C07D217/06;C07D223/04;C07D233/00;C07D233/64;C07D307/00;C07D307/32;C07D307/33;C07D307/62;C07K1/00;C07K5/02;C07K5/06;C07K5/08;C07K7/14;C07K14/81 |
主分类号 |
C07D405/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
