发明名称 |
PROCESS FOR PREPARING CARBAPENEM DERIVATIVES AND PHARMACEUTICALS COMPRISING THE SAME |
摘要 |
<p>Carbapenem derivatives useful as antibacterial agents have the formula <IMAGE> (I) wherein: X represents a hydrogen atom or a methyl group; and Y represents a group of the formula: <IMAGE> +TR <IMAGE> in which: Z represents an oxygen atom or two hydrogen atoms; R1 represents a hydrogen atom, a C1-4 alkyl group, a C1-4 alkanoyl group, or a C1-4 alkanesulfonyl group; R2 represents a hydrogen atom or a hydroxy group, and R3 represents a carbamoyl group; or R2 represents a carbamoyloxy group, and R3 represents a hydrogen atom or a carbamoyl group; R4 represents a hydrogen atom or a C1-4 alkyl group; and <IMAGE> represents a 4-6 membered saturated heterocyclic group in which the indicated nitrogen atom is the only hetero-atom; or a pharmaceutically acceptable salt or ester thereof.</p> |
申请公布号 |
HU194882(B) |
申请公布日期 |
1988.03.28 |
申请号 |
HU19860001736 |
申请日期 |
1986.04.25 |
申请人 |
SANKYO COMPANY LIMITED,JP |
发明人 |
KAWAMOTO,ISAO,JP;ENDRO,ROKURO,JP;IWATA,MASAYUKI,JP |
分类号 |
C07D477/00;A61K31/397;A61K31/40;A61K31/41;A61K31/415;A61K31/425;A61K31/43;A61K31/445;A61K31/495;A61K31/54;A61K31/55;A61P31/04;C07D477/20;C07D499/00;C07D499/88;C07D499/897;(IPC1-7):C07D487/04 |
主分类号 |
C07D477/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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