| 摘要 |
Novel 2- or 3- aryl substituted imidazo[1,2-a]pyridines of formula <CHEM> where X is hydrogen, halogen, hydroxy, alkoxy, benzyloxy, or alkyl, either singularly or in combination; R is H or Ar; R1 is H, CH3 or Ar; Ar is <CHEM> R2 is alkyl; n is 0 or 1 when R is Ar or 1 when R1 is Ar; and m is 2-6, with the proviso that both R and R1 are not Ar at the same time and at least one of R and R1 is Ar. These compounds have local anesthetic properties and are useful as local anesthetic agents, calcium channel blocking agents and antisecretory agents. |
