发明名称 PIPERAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
摘要 The invention relates to new piperazine derivatives of the general formula <IMAGE> I in which R' and R2 each represents 1, 2 or 3 halogen atoms, which may be the same or different, R3 represents a hydrogen atom or 1, 2 or 3 halogen atoms, X represents a hydroxy, C1-4 alkoxy, phenylcarbamoyloxy or C1-4 alkylcarbamoyloxy group, Y represents a hydrogen atom or a C1-3 alkyl group, or X and Y together with the carbon atom to which they are linked represent a carbonyl group, m is 1, 2 or 3, n is 0 or 1, with the proviso that m+n is at most 3, and their acid addition and quaternary ammonium salts. Other features of the invention are processes for the preparation of compounds of formula I, pharmaceutical preparations comprising a compound of formula I.
申请公布号 DE3375690(D1) 申请公布日期 1988.03.24
申请号 DE19833375690 申请日期 1983.06.23
申请人 GIST - BROCADES N.V. 发明人 GOOTJES, JOHAN;VAN DE KAMP, HENDRICUS HYACINTHUS
分类号 C07D295/08;A61K31/495;A61P1/08;C07D295/084;C07D295/10;C07D295/108;(IPC1-7):C07D295/08 主分类号 C07D295/08
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