摘要 |
The invention provides novel compounds represented by general formula (I) wherein the bond represented by the broken line may be a single, double bond or absent; and if the bond is absent, then the nitrogen is substituted with a hydrogen and R<2>; X represents SO2 or C=O of CH2; Y represents -CH(R<4>)-, -N(R<4>)- or -N(R<4>)-CH2-, O; and the meaning of R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, and R<8> are as defined in the application. The compounds are useful as positive modulators of the AMPA-receptor. |
申请人 |
NEUROSEARCH A/S;GOULIAEV, ALEX, HAAHR;LARSEN, MOGENS;VARMING, THOMAS;MATHIESEN, CLAUS;JOHANSEN, TINA, HOLM;SCHEEL-KRUEGER, JOERGEN;OLSEN, GUNNAR, M.;NIELSEN, ELSEBET, OESTERGAARD |
发明人 |
GOULIAEV, ALEX, HAAHR;LARSEN, MOGENS;VARMING, THOMAS;MATHIESEN, CLAUS;JOHANSEN, TINA, HOLM;SCHEEL-KRUEGER, JOERGEN;OLSEN, GUNNAR, M.;NIELSEN, ELSEBET, OESTERGAARD |