发明名称 NOVEL COMPOUNDS AND THEIR USE AS POSITIVE AMPA RECEPTOR MODULATORS
摘要 The invention provides novel compounds represented by general formula (I) wherein the bond represented by the broken line may be a single, double bond or absent; and if the bond is absent, then the nitrogen is substituted with a hydrogen and R<2>; X represents SO2 or C=O of CH2; Y represents -CH(R<4>)-, -N(R<4>)- or -N(R<4>)-CH2-, O; and the meaning of R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, and R<8> are as defined in the application. The compounds are useful as positive modulators of the AMPA-receptor.
申请公布号 WO9942456(A3) 申请公布日期 1999.10.07
申请号 WO1999DK00070 申请日期 1999.02.18
申请人 NEUROSEARCH A/S;GOULIAEV, ALEX, HAAHR;LARSEN, MOGENS;VARMING, THOMAS;MATHIESEN, CLAUS;JOHANSEN, TINA, HOLM;SCHEEL-KRUEGER, JOERGEN;OLSEN, GUNNAR, M.;NIELSEN, ELSEBET, OESTERGAARD 发明人 GOULIAEV, ALEX, HAAHR;LARSEN, MOGENS;VARMING, THOMAS;MATHIESEN, CLAUS;JOHANSEN, TINA, HOLM;SCHEEL-KRUEGER, JOERGEN;OLSEN, GUNNAR, M.;NIELSEN, ELSEBET, OESTERGAARD
分类号 C07D239/74;A61K31/18;A61K31/517;A61K31/535;A61K31/536;A61K31/5415;A61K31/549;A61K31/554;A61P9/10;A61P25/00;A61P25/08;A61P25/14;A61P25/18;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P25/36;A61P43/00;C07C311/37;C07C311/39;C07D239/88;C07D239/90;C07D239/91;C07D265/22;C07D285/24;C07D285/28;C07D285/32;C07D285/36;C07D417/04;C07D417/10;C07D417/12;C07D513/04 主分类号 C07D239/74
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