发明名称 |
Dioxolobenzizoxazole derivatives |
摘要 |
Dioxolobenzisoxazole derivatives of the formula <IMAGE> wherein R1 is a phenyl group which may be substituted with a halogen atom, a lower alkyl group having 1-3 carbon atoms or a lower haloalkyl group, or a thienyl group; R2 is a hydrogen atom or a lower alkyl group having 1-4 carbon atoms; and X and Y which may be the same or different represent a hydrogen atom or a halogen atom, as well as non-toxic salts thereof wherein R2 is a hydrogen atom, a process for preparing the same and a pharmaceutical composition containing the same are disclosed. The derivatives have diuretic and uricosuric activities and, therefore, are useful as a drug for treating hyperuricemia or hypertension.
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申请公布号 |
US4732906(A) |
申请公布日期 |
1988.03.22 |
申请号 |
US19860840680 |
申请日期 |
1986.03.18 |
申请人 |
CHUGAI SEIYAKI KABUSHIKI KAISHA |
发明人 |
KOGA, HIROSHI;DAN, TAKASHI;SATO, HARUHIKO;ONUMA, ETSURO |
分类号 |
A61K31/357;A61K31/42;A61P7/10;C07D261/00;C07D317/00;C07D498/04;(IPC1-7):C07D261/20 |
主分类号 |
A61K31/357 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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