发明名称 Dioxolobenzizoxazole derivatives
摘要 Dioxolobenzisoxazole derivatives of the formula <IMAGE> wherein R1 is a phenyl group which may be substituted with a halogen atom, a lower alkyl group having 1-3 carbon atoms or a lower haloalkyl group, or a thienyl group; R2 is a hydrogen atom or a lower alkyl group having 1-4 carbon atoms; and X and Y which may be the same or different represent a hydrogen atom or a halogen atom, as well as non-toxic salts thereof wherein R2 is a hydrogen atom, a process for preparing the same and a pharmaceutical composition containing the same are disclosed. The derivatives have diuretic and uricosuric activities and, therefore, are useful as a drug for treating hyperuricemia or hypertension.
申请公布号 US4732906(A) 申请公布日期 1988.03.22
申请号 US19860840680 申请日期 1986.03.18
申请人 CHUGAI SEIYAKI KABUSHIKI KAISHA 发明人 KOGA, HIROSHI;DAN, TAKASHI;SATO, HARUHIKO;ONUMA, ETSURO
分类号 A61K31/357;A61K31/42;A61P7/10;C07D261/00;C07D317/00;C07D498/04;(IPC1-7):C07D261/20 主分类号 A61K31/357
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