发明名称 DOPAMINE-BETA-HYDROXYLASE INHIBITOR
摘要 Compounds of Formula (I): <CHEM> in which X is H, F, Cl, Br, I, C 1-4alkyl, CN NO2, SO2NH2, COOH, OH, CHO, C 1-4alkoxy, CH2OH, CF3, SO2CH3, SO2CF3, or CO2C aH 2a+1 wherein a is 1-5, or any synthetically accessible combination thereof of up to 5 substituents, n is 0-5, R and R' independently are H or C 1-4alkyl, or any pharmaceutically acceptable salt or hydrate thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as dopamine- beta -hydroxylase inhibitors.
申请公布号 JPS6363670(A) 申请公布日期 1988.03.22
申请号 JP19870212656 申请日期 1987.08.25
申请人 SMITHKLINE BECKMAN CORP 发明人 JIYOSEFU ARAN FUINKERUSUTAIN;ROURENSU AIBAN KURUSU;TOOMASU BURENTO REONARUDO
分类号 C07D295/14;A61K31/41;A61P1/04;A61P7/10;A61P9/04;A61P9/08;A61P9/12;A61P25/00;A61P43/00;C07D249/12;C07D295/15 主分类号 C07D295/14
代理机构 代理人
主权项
地址