Hydroxybutenolide derivatives, production and use thereof.

摘要

The present invention relates to a compound of the formula: <CHEM> wherein Y is a chemical bond, oxygen atom, phenyleneoxy, or oxyphenyleneoxy; R<1> is hydrogen or hydrocarbon residue; and R<2> is hydrocarbon residue having two or more carbon atoms, producution and use thereof. The compound (I) of the present invention has an anti-oxidation activity and activities of preventing or improving functional disorders due to biologically active oxygen species, thus being useful as a pharmaceutical agent for prophylaxis and therapy of disorders in the circulatory system.