发明名称 XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME
摘要 XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME Xanthone derivatives of the formula (I): (I) (wherein W, X, Y and Z which may be the same or different represent a hydrogen atom, a halogen atom or a lower alkyl group having 1 to 4 carbon atoms; A is a hydrogen atom or may bind to X or Y to form a cyclic methylene chain; B is a hydroxymethyl group, a lower alkoxycarbonyl group having 1 to 4 carbon atoms, or a carboxyl group, provided that W is neither a hydrogen atom nor a 7-position methyl group when X, Y and Z are each a hydrogen atom, and A is a hydrogen atom and B is a carboxyl group or a lower alkoxycarbonyl group), as well as intoxic salts thereof when B is a carboxyl group, and a process for preparing the same are disclosed. The compounds of formula (I) in accordance with the present invention are useful as diuretics having uricosuric activity and can be used in the treatment of edema or hypertension.
申请公布号 CA1234126(A) 申请公布日期 1988.03.15
申请号 CA19850491080 申请日期 1985.09.18
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 KOGA, HIROSHI;MORI, TAKASHI;DAN, TAKASHI;AKIMA, MICHITAKA
分类号 A61K31/35;C07D311/86;C07D493/04 主分类号 A61K31/35
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