| 摘要 |
<p>Compounds of structure (I), in which R1 is hydrogen, C¿1-6?alkyl, C1-6alkoxyl-C1-6alkyl, C3-6cycloalkyl, C3-6cycloalkyl-C1-6alkyl, phenyl, phenyl-C1-6alkyl, the phenyl groups being optionally substituted; R?2¿ is C¿1-6?alkyl, C3-6cycloalkyl, C3-6cycloalkyl-C1-6alkyl, phenyl, phenylC1-6alkyl or phenyl substituted by 1-3 radicals selected from C1-6alkyl, C1-6alkoxy, amino C1-6alkylthio, halogen, cyano, hydroxy, carbamoyl, carboxy, C1-6alkanoyl, trifluoromethyl and nitro; R?3¿ is C¿1-6?alkyl, phenyl, C1-6alkoxy, C1-6alkylthio, C1-6alkanoyl, amino, C1-6alkylamino, di-C1-6alkylamino, halogen, trifluoromethyl or cyano; and n is 0, 1 or 2, or pharmaceutically acceptable salts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy for the inhibition of gastric acid secretion.</p> |
