| 摘要 |
PROBLEM TO BE SOLVED: To obtain an active oxygen-eliminating agent excellent in an eliminating action on active oxygen generated in a living body, high in safety, and capable of being used for foods, cosmetics, etc. SOLUTION: This active oxygen-eliminating agent comprises an oligogalacturonic acid-transition metal complex of the formula (M is a transition metal ion; (n), (o), (p) are each 0 or a natural number). The oligogalacturonic acid is obtained by hydrolyzing pectin with an enzyme, ultra-filtering the hydrolysate, and subsequently purifying the filtered product by a gel filtration method, etc., into fractions having different polymerization degrees, respectively, preferably a fraction having a polymerization degree of 1-5. The obtained oligogalacturonic acid is mixed with a transition metal (e.g. Fe) salt such as a hydrochloride or a nitrate to obtain the objective active oxygen-eliminating agent. The compound of the formula and the transition metal are composed in a ratio of 1:2 to 1:6. The active oxygen-eliminating agent is preferably compounded to a cosmetic in an amount of 0.01-10wt.%, and the agent is orally administered at a daily dose of 10-100mg for an adult divided in one to several portions or injected at a dose of 5-500mg in medicines. |
