Process for preparation of samples for analysis.

摘要

There is disclosed herein an automated sample preparation system for chemical assay of samples of materials. The sample preparation system includes a sample preparation chamber (12) which includes a removable cup (12) for taking to the location of solid or very viscous samples. The cup may be attached in sealing relationship to a cap (14)through which extends various utilities such as a mixer/grinder (30, 34) to grind solid samples and mix non-homogeneous samples, a fill pipe (26) to pump in liquid samples, an effluent pipe (20) in the sump of the cup to allow pump of samples and solvents and a nozzle (28) to allow liquids to be sprayed against the walls. A sample metering valve (36) associated with the sample preparation chamber allows a known volume of sample to be isolated so that solvent may be pumped in to dilute the sample to a user defined concentration. A reversible pump (84) is coupled by a pair of manifolds (94,96) which are themselves coupled by solenoid operated valves (e.g. 90, 92) to various sources of solvents (132), pressurized gas (104), vacuum (108), water (112), the sample preparation chamber (12) and the assay system. A control system (98) coordinates the operation of all remotely controllable units in the system to allow the user to customize various sample preparation processes. A number of different sample preparation processes are disclosed using the elements of the system to prepare different types of samples for analysis by systems such as liquid chromatography systems.