发明名称 ALDOSE REDUCTASE INHIBITING 5-(2- ALKOXYPHENYL)THIAZOLIDINEDIONES
摘要 <p>ALDOSE REDUCTASE INHIBITING 5-(2- ALKOXYPHENYL)THIAZOLIDINEDIONES A series of 5-(2-alkoxyphenyl)thiazolidinediones and pharmaceutically acceptable salts thereof useful as hypoglycemic agents, aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications; intermediates therefore; and processes for preparation of said compounds. (IV) wherein R is alkyl having from one to four carbon atoms; X is fluoro, chloro or bromo; and Y is hydrogen, chloro, lower alkyl or lower alkoxy.</p>
申请公布号 CA1233470(A) 申请公布日期 1988.03.01
申请号 CA19840445291 申请日期 1984.01.13
申请人 PFIZER INC. 发明人 SCHNUR, RODNEY C.
分类号 C12N9/99;A61K31/425;A61K31/426;A61P3/08;A61P3/10;A61P43/00;C07C43/225;C07C45/51;C07C59/64;C07D277/20;C07D277/34;(IPC1-7):C07D277/34 主分类号 C12N9/99
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