摘要 |
<p>ALDOSE REDUCTASE INHIBITING 5-(2- ALKOXYPHENYL)THIAZOLIDINEDIONES A series of 5-(2-alkoxyphenyl)thiazolidinediones and pharmaceutically acceptable salts thereof useful as hypoglycemic agents, aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications; intermediates therefore; and processes for preparation of said compounds. (IV) wherein R is alkyl having from one to four carbon atoms; X is fluoro, chloro or bromo; and Y is hydrogen, chloro, lower alkyl or lower alkoxy.</p> |