发明名称 |
Mutant human T cell line producing immunosuppressive factor and method for obtaining such mutants |
摘要 |
A stable mutant human T cell line is disclosed which secretes a high titer suppressor inducer factor. This suppressor inducer factor in turn induces production of a T cell suppressor factor which suppressed mitogen-induced T cell proliferation at high dilution. Also disclosed is a general method for mutating lymphoblastoid cell lines to yield mutants secreting enhanced levels of lymphokines.
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申请公布号 |
US4728614(A) |
申请公布日期 |
1988.03.01 |
申请号 |
US19840586515 |
申请日期 |
1984.03.05 |
申请人 |
ORTHO PHARMACEUTICAL |
发明人 |
LAU, CATHERINE Y. |
分类号 |
A61K35/12;A61K38/00;A61K38/11;C07K14/52;C12N5/0789;(IPC1-7):C12N5/00;C12N15/00;A61K37/02;C12R1/91 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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