发明名称 |
PHARMACEUTICAL COMPOSITIONS OF CLONAZEPAM AND METHODS OF USE THEREOF |
摘要 |
The present invention includes benzodiazepine compositions formulated for intranasal administration, comprising a binary solvent system comprising a first solvent in which the benzodiazepine is soluble, the first solvent capable of penetrating nasal mucosal tissue, and a second solvent in which the benzodiazepine in less soluble. The compositions of the present invention may be used to treat a variety of disorders including, but not limited to, panic attacks, muscle spasms, anxiety, and seizures. In one aspect, the present invention relates to a fast-acting, clonazepam composition for transnasal administration that can be used for the treatment of seizure clusters. |
申请公布号 |
WO2008027357(A3) |
申请公布日期 |
2008.04.17 |
申请号 |
WO2007US18877 |
申请日期 |
2007.08.27 |
申请人 |
JAZZ PHARMACEUTICALS;JAMIESON, GENE;DES JARDIN, MICHAEL;ALLPHIN, CLARK |
发明人 |
JAMIESON, GENE;DES JARDIN, MICHAEL;ALLPHIN, CLARK |
分类号 |
A61K47/10;A61K31/5513;A61K47/14;A61K47/22;A61P25/08 |
主分类号 |
A61K47/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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