PROCESS FOR PREPARING SUBSTITUTED ANTRA SQUARE BRACKETS OPEN 1,9-CD SQUARE BRACKETS CLOSED PYRAZOL-6-(2H)-ONE DERIVATIVES

摘要

An improved process for producing anthra[1,9-cd]pyrazol-6(2H)-ones from 1,4-dichloro-5,8-disubstituted 9,10-anthracenediones. The process produces higher yields by using a new combination of protecting groups on the compounds which allows for easier and cleaner chromatographic resolution. The compounds produced have antibacterial, antifungal, antileukemic, and antitumor activity.