| 摘要 |
A method of monitoring fermentation in a fermentation broth. The method is conducted in such a way that the total number of particles in a sample from the fermentation broth is determined by means of a device giving an optical density reading which is a measure of the total number of particles present, that said sample is mixed with an excess of labelled specific antibodies directed against a product chosen from the group consisting of an inoculum, a desired fermentation product and an important contaminant, that the number of particles consisting of product bound to the labelled specific antibody is determined with the aid of the label used and is compared to the determined total number of particles, and that this comparison indicates if any particles contaminating the fermentation are present in the fermentation broth. The method can be performed in a continuous manner, and with computer assistance and the use of a FACS, also automatically. |
