PROCESS FOR THE PREPARATION OF NEUCLEOSIDE DERIVATIVE

摘要

Nucleoside derivative (I) was prepared by reacting 1-0-alkyl2-0- acylglycero-3-phosphate (VIII) with nucleotide (III) which was produced from morpholidate (VI) or P-nucleocide-5'-P2-diphenyl pirophophate (VII). Also, nucleoside (I) was prepared by reacting nucleotide (III) with phospholiped (VIII) which was produced from phospholipid morpholidate (IX) or P'-glycerol-5'-P2-diphenyl pirophosphate (X).