发明名称 |
Process for the preparation of indoles |
摘要 |
A process for producing an indole which comprises reacting an aniline and a diol in the presence of a catalyst to produce a reaction mixture containing the indole, unreacted aniline and by-products, condensing the reaction mixture to obtain a liquid reaction product, recovering the unreacted aniline from the liquid reaction product, reducing the contents of specified by-products in the recovered aniline below specified levels and reutilizing the resulting recovered aniline. To reduce the contents of the specified by-products in the recovered aniline below specified levels, it is preferred to subject the liquid reaction product or an aniline fraction separated therefrom to a heat-treatment and then to distillation. In the above manner, the recovered aniline can be reutilized in the reaction without causing the activity of the catalyst to deteriorate.
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申请公布号 |
US4727161(A) |
申请公布日期 |
1988.02.23 |
申请号 |
US19850798919 |
申请日期 |
1985.11.15 |
申请人 |
MITSUI TOATSU CHEMICALS, INCORPORATED |
发明人 |
YAMAUCHI, ATSUYOSHI;IGUCHI, SEIYA;ONO, YUZO;KIMURA, HIROSHII;MORITA, SATOSHI |
分类号 |
C07D209/04;C07D209/08;(IPC1-7):C07D209/08;C07D209/12;C07C85/26 |
主分类号 |
C07D209/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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