发明名称 |
PROCEDIMENTO STEREOSPECIFICO PER PREPARARE AZETIDINONI |
摘要 |
<p>Chiral azetidinones II (R1 optionally substituted phenyl, R2 = C1-C4 alkyl or aryl, R3 = H or an N-protecting group) are prepared by reacting compound III (R4 = carboxy protecting group) with an organometallic derivative and treating the resultant dianion with a compound IV. The azetidinones II are stereospecifically prepared by the above process and may be converted to azetidinones VIII (R5 = hydroxy protecting group), useful in the preparation of penems. <IMAGE></p> |
申请公布号 |
IT1190381(B) |
申请公布日期 |
1988.02.16 |
申请号 |
IT19850021263 |
申请日期 |
1985.06.21 |
申请人 |
CONSIGLIO NAZIONALE DELLE RICERCHE;FARMITALIA CARLO ERBA SPA |
发明人 |
CAINELLI GIANFRANCO;CONTENTO MICHELE;GIACOMINI DARIA;PANUNZIO MAURO;FRANCESCHI GIOVANNI |
分类号 |
C07D205/08;C07D477/00;C07D487/08;C07D499/06;C07D499/88;C07D499/897;C07F7/10;C07F7/18;(IPC1-7):C07F/ |
主分类号 |
C07D205/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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