发明名称 UN PROCEDIMIENTO PARA PREPARAR DERIVADOS DE 3-AMINO-4-OXO-2,3,4,5-BENZOXAPINA
摘要 <p>Novel condensed seven-membered ring compounds of the formula: <CHEM> [wherein R<1> and R<2> are independently hydrogen, halogen, trifluoromethyl, lower alkyl or lower alkoxy, or both jointly form tri- or tetramethylene; R<3> and R<5> are independently hydrogen lower alkyl or aralkyl; R<4> is hydrogen or lower alkyl; R<6> is a condensed or non-condensed hetero-alicyclic containing at least one atom of N, O and S as a ring-forming atom which may be substituted; A is an alkylene chain; n is 1 or 2] and salts thereof. These compounds exhibit inhibitory activity on angiotensin converting enzyme and so forth, and are of value as an agent for diagnosis, prevention and treatment of circulatory diseases, such as hypertension, cardiopathy and cerebral apoplexy.</p>
申请公布号 ES557636(D0) 申请公布日期 1988.02.16
申请号 ES19550007636 申请日期 1987.07.29
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人
分类号 A61K31/445;A61K31/55;A61K31/554;A61K38/00;A61P9/12;C07D209/48;C07D211/18;C07D211/22;C07D211/32;C07D281/10;C07D417/04;C07D417/12;C07K5/02;(IPC1-7):C07D417/12;C07D211/34;C07D281/00 主分类号 A61K31/445
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