摘要 |
A new method of treating a patient suffering smooth muscle spasm comprises administering to the patient an effective amount of anti-spasmodic compound having the general formula: <IMAGE> where R is selected from the group consisting of: <IMAGE> wherein W is CH2, NH, O or S, <IMAGE> wherein Y is an alicyclic ring ring having 3-12 carbon atoms, and <IMAGE> the total number of carbon atoms in R is equal to or less than 20. Furthermore, m is an integer from 1 to 4, n is an integer from 1 to 4, p is an integer from 1 to 4 and q is an integer from 1 to 4. X may be nonexistent or may be 0, S, NH or CH2 or salts thereof. However, when X is nonexistent the terminal group in both the n-chain and the p-chain is a methyl group provided that a is zero or 1 and when a is 1, X is selected from the group consisting of 0, S, and CH2 and n and p are integers from 1 to 4; and when a is 0 then X is nonexistent and n and p are integers from 1 to 4 and the terminal group in both the n-chain and the p-chain is methyl; and pharmaceutically acceptable salts thereof.
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