发明名称 |
NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF |
摘要 |
Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein -------, R1, R2, R5, A and L are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia. |
申请公布号 |
EP3035940(A1) |
申请公布日期 |
2016.06.29 |
申请号 |
EP20140837132 |
申请日期 |
2014.08.22 |
申请人 |
SAGE THERAPEUTICS, INC. |
发明人 |
MARTINEZ BOTELLA, GABRIEL;HARRISON, BOYD L.;ROBICHAUD, ALBERT JEAN;SALITURO, FRANCESCO GERALD;HERR, ROBERT JASON;KARGBO, ROBERT BORBO |
分类号 |
A61K31/58;A61K31/57;A61P23/00;A61P25/08;C07J43/00 |
主分类号 |
A61K31/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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