发明名称 |
CL-1957E antibiotic compound and its production |
摘要 |
A purified isolate of an actinomycete identified as ATCC 39366 is capable of producing the antimicrobial compound CL-1957E which also exhibits antitumor properties. The antimicrobial compound CL-1957E is produced by cultivating isolate ATCC 39366 under aerobic conditions in a culture medium containing assimilable sources of carbon and nitrogen until a substantially quantity of the CL-1957E compound is produced, and subsequently isolating the CL-1957E compound. The antibiotic compound CL-1957E and pharmaceutical compositions comprising this substance together with a pharmaceutically acceptable carrier is also disclosed, as are methods of treating microbial infections and tumors in mammals, employing these pharmaceutical compositions.
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申请公布号 |
US4725621(A) |
申请公布日期 |
1988.02.16 |
申请号 |
US19860835825 |
申请日期 |
1986.03.03 |
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
BUNGE, RICHARD H.;FRENCH, JAMES C.;HURLEY, TIMOTHY R.;WILLMER, NEIL E. |
分类号 |
C07D309/30;(IPC1-7):A61K31/365 |
主分类号 |
C07D309/30 |
代理机构 |
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代理人 |
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地址 |
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