| 摘要 |
NEW MATERIAL:A T-cell activation factor having following physical and chemical properties: molecular weight: about 17,500 (according to the SDS-PAGE method), isoelectric point: 9.5+ or -0.3 (according to the chromato-focusing method), amino acid composition: Ala 1.00, Arg 0.60, Asp/Asn 0.38, Glu/Gln 0.75, Gly 0.59, His 0.21, Ile 0.42, Leu 0.46, Lys 1.53, Met 0.25, Phe 0.16, Pro 0.46, Ser 0.97, Thr 0.56, Tyr 0.29, Val 0.36; 42 amino acids from the amino terminal have the sequence of the formula. USE:Therapeutic agent for cancers. PREPARATION:For example, a cell strain such as human B lymphoma cell SSY strain or Burkit lymphoma Namarva strain is cultivated in an appropriate medium usually at 30-40 deg.C for 2-4 days and the factor is collected from the culture mixture. |
