| 摘要 |
<p>A stable antiplaque dentifrice with improved foaming and fluoride chemical stability containing an antiplaque quaternary ammonium compound, a betaine surfactant to improve foaming without inactivating the antibacterial and antiplaque activity of the quaternary ammonium compound, a humectant selected from the group consisting of polyethylene glycol, sorbitol and mixtures thereof, a nonionic gelling agent, such as hydroxyethylcellulose, and preferably a fluorine-containing compound capable of providing a fluoride ion, in an aqueous vehicle containing a dental abrasive. The sorbitol component, which stabilises the betaine quaternary ammonium system, also improves long term fluoride chemical stability of the dentifrice. In a sole polyethylene glycol humectant, a small amount of glycerin, as low as 1%, may be utilised to improve long term fluoride stability, without adversely affecting the cosmetic stability of the dentifrice.</p> |
