| 摘要 |
The invention provides the use of a compound of the formula [E-DHC] (I) or a non-toxic pharmaceutically acceptable salt thereof, wherein [E] is an estrogen and [DHC] is the reduced, biooxidizable, blood-brain barrier-penetrating, lipoidal form of a dihydropyridine @@@pyridinium salt redox carrier in the preparation of a medicament for treating male sexual dysfunction. Compositions for use in the subject method are also disclosed. A preferred compound for use in the method and compositions is an estradiol derivative, namely, 17 beta -[(1-methyl-1,4-dihydro-3-pyridinyl)carbonyloxy]estra-1,3,5(1O)-trien- 3-ol. |
